HIV Target gene Detail Information

> RBL1 Gene Search Result

Gene Information

Gene Name	RBL1
Gene ID	5933
Gene Full Name	RB transcriptional corepressor like 1
Gene Alias	PRB1; p107; CP107
Transcripts	ENSG00000080839
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nucleoplasm;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins
Gene Function	Suppressor gene
Uniport_ID	P28749
HGNC ID	HGNC:9893
VEGA ID	OTTHUMG00000032406
OMIM ID	116957
String ID	9606.ENSP00000362768
PharmGKB ID	PA34257

Target gene [RBL1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4000585	chr20	251	54	56	361	View
4000799	chr20	69	192	18	279	View
4001170	chr20	182	18	1	201	View
4001892	chr20	107	17		124	View
4002284	chr20	71	30		101	View
4004660	chr20	34	7		41	View
4005279	chr20	34			34	View
4006494	chr20	17	6	1	24	View
4006831	chr20	20	2		22	View
4007620	chr20	16	2		18	View
4010521	chr20	5	3		8	View
4010735	chr20	8			8	View
4011603	chr20	3	3		6	View
4012296	chr20	5			5	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of RBL1 expression and immune infiltrating cell level correlation result in HIV+ samples
RBL1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).