HIV Target gene Detail Information

> RBKS Gene Search Result

Gene Information

Gene Name	RBKS
Gene ID	64080
Gene Full Name	ribokinase
Gene Alias	RK; RBSK
Transcripts	ENSG00000171174
Virus	HIV
Gene Type	protein coding
HPA Location Info	Cytosol;Nucleoplasm;
HPA Protein Class Info	Enzymes, Predicted intracellular proteins
Uniport_ID	Q9H477
HGNC ID	HGNC:30325
VEGA ID	OTTHUMG00000097833
OMIM ID	611132
String ID	9606.ENSP00000306817
PharmGKB ID	PA134951602

Target gene [RBKS] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4000605	chr2	87	63	197	347	View
4000680	chr2	56	69	196	321	View
4005611	chr2	31			31	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of RBKS expression and immune infiltrating cell level correlation result in HIV+ samples
RBKS expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of RBKS expression and immune infiltrating cell level correlation result in HIV+ samples
RBKS expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).