HIV Target gene Detail Information

> RBBP6 Gene Search Result

Gene Information

Gene Name	RBBP6
Gene ID	5930
Gene Full Name	RB binding protein 6, ubiquitin ligase
Gene Alias	PACT; MY038; P2P-R; RBQ-1; SNAMA
Transcripts	ENSG00000122257
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nuclear speckles;
HPA Protein Class Info	Enzymes, Predicted intracellular proteins
Uniport_ID	Q7Z6E9
HGNC ID	HGNC:9889
VEGA ID	OTTHUMG00000096991
OMIM ID	600938
String ID	9606.ENSP00000317872
PharmGKB ID	PA34253

Target gene [RBBP6] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4003178	chr16	67			67	View
4009618	chr16	10	1		11	View
4010955	chr16	2	6		8	View
4011205	chr16	1	6		7	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of RBBP6 expression and immune infiltrating cell level correlation result in HIV+ samples
RBBP6 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of RBBP6 expression and immune infiltrating cell level correlation result in HIV+ samples
RBBP6 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).