HBV Target gene Detail Information

> RB1CC1 Gene Search Result


Gene Information
Gene Name RB1CC1
Gene ID 9821
Gene Full Name RB1 inducible coiled-coil 1
Gene Alias CC1; ATG17; FIP200; PPP1R131
Transcripts ENSG00000023287
Virus HBV
Gene Type protein coding
HPA Location Info Cytosol;Nuclear membrane;
HPA Protein Class Info Predicted intracellular proteins
Gene Function Suppressor gene
Uniport_ID Q8TDY2
HGNC ID HGNC:15574
VEGA ID OTTHUMG00000164268
OMIM ID 606837
String ID 9606.ENSP00000025008
PharmGKB ID PA34248
Target gene [RB1CC1] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1009806 chr8 14 14 View
1009807 chr8 14 14 View
1009912 chr8 14 14 View
1009913 chr8 14 14 View
1010001 chr8 14 14 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE114783 (GEO) Chronic HBV (CHB) infection 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Hepatocellular carcinoma 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Liver cirrhosis 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: GSE114783

HeatMap of cell type fractions in all samples Lollipop of RB1CC1 expression and immune infiltrating cell level correlation result in HBV+ Chronic HBV (CHB) infection samples
RB1CC1 expression: Low -> High
Lollipop of RB1CC1 expression and immune infiltrating cell level correlation result in HBV+ Liver cirrhosis samples Lollipop of RB1CC1 expression and immune infiltrating cell level correlation result in HBV+ Hepatocellular carcinoma samples

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of RB1CC1 expression and immune infiltrating cell level correlation result in HBV+ samples
RB1CC1 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).