Home
Virus
Gene
Disease
Dataset
Download
Help
 
HBV Target gene Detail Information

> RB1 Gene Search Result


Gene Information
Gene Name RB1
Gene ID 5925
Gene Full Name RB transcriptional corepressor 1
Gene Alias RB; pRb; OSRC; pp110; p105-Rb; PPP1R130
Transcripts ENSG00000139687
Virus HBV
Gene Type protein coding
HPA Location Info Nucleoplasm;
HPA Protein Class Info Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins
Gene Function Suppressor gene
Uniport_ID P06400
HGNC ID HGNC:9884
VEGA ID OTTHUMG00000016900
OMIM ID 614041
String ID 9606.ENSP00000267163
Drugbank ID BE0002123
PharmGKB ID PA295
Target gene [RB1] related to virus gene/protein/region
ID PMID Mutation Gene/Protein/Region Description Detail
1 22962577 C1653T
C Promoter
G
C
 View

Target gene [RB1] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1003097 chr16 157 10 167 View
1006180 chr21 31 9 2 42 View
1008694 chr12 8 11 19 View
1012224 chr13 2 5 7 View
1012875 chr4 1 5 6 View
1013057 chr8 3 2 5 View
1013488 chr4 1 4 5 View
1018491 chr12 0 View
1400506 chr12 15 4 19 View
1404935 chr8 1 1 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of RB1 expression and immune infiltrating cell level correlation result in HBV+ samples
RB1 expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).