HIV Target gene Detail Information

> RASSF5 Gene Search Result

Gene Information

Gene Name	RASSF5
Gene ID	83593
Gene Full Name	Ras association domain family member 5
Gene Alias	RAPL; Maxp1; NORE1; NORE1A; NORE1B; RASSF3
Transcripts	ENSG00000266094
Virus	HIV
Gene Type	protein coding
HPA Location Info
HPA Protein Class Info	Predicted intracellular proteins, RAS pathway related proteins
Gene Function	Suppressor gene
Uniport_ID	Q8WWW0
HGNC ID	HGNC:17609
VEGA ID	OTTHUMG00000184616
OMIM ID	607020
String ID	9606.ENSP00000462099
PharmGKB ID	PA134958571

Target gene [RASSF5] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4015943	chr1				0	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of RASSF5 expression and immune infiltrating cell level correlation result in HIV+ samples
RASSF5 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of RASSF5 expression and immune infiltrating cell level correlation result in HIV+ samples
RASSF5 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).