HIV Target gene Detail Information

> RASGRP1 Gene Search Result

Gene Information

Gene Name	RASGRP1
Gene ID	10125
Gene Full Name	RAS guanyl releasing protein 1
Gene Alias	RASGRP; CALDAG-GEFI; CALDAG-GEFII
Transcripts	ENSG00000172575
Virus	HIV
Gene Type	protein coding
HPA Location Info	Cytosol;Plasma membrane;
HPA Protein Class Info	Disease related genes, Predicted intracellular proteins, RAS pathway related proteins
Uniport_ID	O95267
HGNC ID	HGNC:9878
VEGA ID	OTTHUMG00000172379
OMIM ID	603962
String ID	9606.ENSP00000310244
PharmGKB ID	PA34240

Target gene [RASGRP1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4002783	chr15	22	6	52	80	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of RASGRP1 expression and immune infiltrating cell level correlation result in HIV+ samples
RASGRP1 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of RASGRP1 expression and immune infiltrating cell level correlation result in HIV+ samples
RASGRP1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).