HTLV1 Target gene Detail Information

> RASGEF1B Gene Search Result

Gene Information

Gene Name	RASGEF1B
Gene ID	153020
Gene Full Name	RasGEF domain family member 1B
Gene Alias	GPIG4
Transcripts	ENSG00000138670
Virus	HTLV1
Gene Type	protein coding
HPA Location Info	Nucleoplasm;Vesicles;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID	Q0VAM2
HGNC ID	HGNC:24881
VEGA ID	OTTHUMG00000160890
OMIM ID	614532
String ID	9606.ENSP00000264400
PharmGKB ID	PA134927621

Target gene [RASGEF1B] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
6004737	chr4	96	8	2	106	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE55851 (GEO)	Adult T-cell leukemia	21	Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)
GSE29312 (GEO)	HTLV-1 associated myelopathy	39	Normal (9), Asymptomatic carriers (HTLV1+)(20), HTLV-1-associated myelopathy (HTLV1+)(10)
GSE29332 (GEO)	HTLV-1 associated myelopathy	35	Normal (8), Asymptomatic carriers (HTLV1+)(17), HTLV-1-associated myelopathy (HTLV1+)(10)

> Dataset: GSE55851
HeatMap of cell type fractions in all samples	Lollipop of RASGEF1B expression and immune infiltrating cell level correlation result in HTLV1+ samples
RASGEF1B expression: Low -> High

> Dataset: GSE29312
HeatMap of cell type fractions in all samples	Lollipop of RASGEF1B expression and immune infiltrating cell level correlation result in HTLV1+ samples
RASGEF1B expression: Low -> High

> Dataset: GSE29332
HeatMap of cell type fractions in all samples	Lollipop of RASGEF1B expression and immune infiltrating cell level correlation result in HTLV1+ samples
RASGEF1B expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).