HTLV1 Target gene Detail Information

> RASGEF1A Gene Search Result

Gene Information

Gene Name	RASGEF1A
Gene ID	221002
Gene Full Name	RasGEF domain family member 1A
Gene Alias	CG4853
Transcripts	ENSG00000198915
Virus	HTLV1
Gene Type	protein coding
HPA Location Info	Golgi apparatus;
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	Q8N9B8
HGNC ID	HGNC:24246
VEGA ID	OTTHUMG00000018025
OMIM ID	614531
String ID	9606.ENSP00000363583
PharmGKB ID	PA134884893

Target gene [RASGEF1A] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
6021519	chr10	6			6	View
6029018	chr10	1			1	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE55851 (GEO)	Adult T-cell leukemia	21	Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)
GSE29312 (GEO)	HTLV-1 associated myelopathy	39	Normal (9), Asymptomatic carriers (HTLV1+)(20), HTLV-1-associated myelopathy (HTLV1+)(10)
GSE29332 (GEO)	HTLV-1 associated myelopathy	35	Normal (8), Asymptomatic carriers (HTLV1+)(17), HTLV-1-associated myelopathy (HTLV1+)(10)

> Dataset: GSE55851
HeatMap of cell type fractions in all samples	Lollipop of RASGEF1A expression and immune infiltrating cell level correlation result in HTLV1+ samples
RASGEF1A expression: Low -> High

> Dataset: GSE29312
HeatMap of cell type fractions in all samples	Lollipop of RASGEF1A expression and immune infiltrating cell level correlation result in HTLV1+ samples
RASGEF1A expression: Low -> High

> Dataset: GSE29332
HeatMap of cell type fractions in all samples	Lollipop of RASGEF1A expression and immune infiltrating cell level correlation result in HTLV1+ samples
RASGEF1A expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).