HIV Target gene Detail Information

> RASA1 Gene Search Result

Gene Information

Gene Name	RASA1
Gene ID	5921
Gene Full Name	RAS p21 protein activator 1
Gene Alias	GAP; PKWS; RASA; p120; CMAVM; CM-AVM; RASGAP; p120GAP; p120RASGAP
Transcripts	ENSG00000145715
Virus	HIV
Gene Type	protein coding
HPA Location Info
HPA Protein Class Info	Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins
Uniport_ID	P20936
HGNC ID	HGNC:9871
VEGA ID	OTTHUMG00000162605
OMIM ID	139150
String ID	9606.ENSP00000274376
PharmGKB ID	PA34232

Target gene [RASA1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4007465	chr5	7	6	6	19	View
4009629	chr5	7	2	2	11	View
4012763	chr5	3	1		4	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of RASA1 expression and immune infiltrating cell level correlation result in HIV+ samples
RASA1 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of RASA1 expression and immune infiltrating cell level correlation result in HIV+ samples
RASA1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).