HBV Target gene Detail Information

> RARB Gene Search Result

Gene Information

Gene Name	RARB
Gene ID	5915
Gene Full Name	retinoic acid receptor beta
Gene Alias	HAP; RRB2; NR1B2; MCOPS12; RARbeta1
Transcripts	ENSG00000077092
Virus	HBV
Gene Type	protein coding
HPA Location Info	Nucleoplasm;
HPA Protein Class Info	Cancer-related genes, Disease related genes, FDA approved drug targets, Nuclear receptors, Predicted intracellular proteins, Transcription factors
Gene Function	Suppressor gene
Uniport_ID	P10826
HGNC ID	HGNC:9865
VEGA ID	OTTHUMG00000130480
OMIM ID	180220
String ID	9606.ENSP00000332296
Drugbank ID	BE0000206
Drug (Cytoscape Annotation)	Bexarotene
PharmGKB ID	PA34226

Target gene [RARB] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1011786	chr3	3	5		8	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of RARB expression and immune infiltrating cell level correlation result in HBV+ samples
RARB expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).