HIV Target gene Detail Information

> RAPGEF5 Gene Search Result

Gene Information

Gene Name	RAPGEF5
Gene ID	9771
Gene Full Name	Rap guanine nucleotide exchange factor 5
Gene Alias	GFR; REPAC; MR-GEF
Transcripts	ENSG00000136237
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nucleoplasm;Nuclear bodies;
HPA Protein Class Info	Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins
Uniport_ID	Q92565
HGNC ID	HGNC:16862
VEGA ID	OTTHUMG00000152525
OMIM ID	609527
String ID	9606.ENSP00000343656
PharmGKB ID	PA134902361

Target gene [RAPGEF5] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4016534	chr7				0	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of RAPGEF5 expression and immune infiltrating cell level correlation result in HIV+ samples
RAPGEF5 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).