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HIV Target gene Detail Information

> RAP1B Gene Search Result


Gene Information
Gene Name RAP1B
Gene ID 5908
Gene Full Name RAP1B, member of RAS oncogene family
Gene Alias K-REV; RAL1B
Transcripts ENSG00000127314
Virus HIV
Gene Type protein coding
HPA Location Info
HPA Protein Class Info Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins
Uniport_ID P61224
HGNC ID HGNC:9857
VEGA ID OTTHUMG00000133660
OMIM ID 179530
String ID 9606.ENSP00000250559
PharmGKB ID PA34219
Target gene [RAP1B] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
4001451 chr12 91 68 4 163 View
4001664 chr12 137 4 1 142 View
4002666 chr12 13 11 61 85 View
4006737 chr12 15 8 23 View
4010787 chr12 5 1 2 8 View
4012877 chr12 1 3 4 View
4014683 chr12 2 2 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE17372 (GEO) AIDS-associated lymphoma 17 AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO) HIV-infected disease 44 HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372

HeatMap of cell type fractions in all samples Lollipop of RAP1B expression and immune infiltrating cell level correlation result in HIV+ samples
RAP1B expression: Low -> High

> Dataset: GSE50834

HeatMap of cell type fractions in all samples Lollipop of RAP1B expression and immune infiltrating cell level correlation result in HIV+ samples
RAP1B expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).