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HBV Target gene Detail Information

> RANBP2 Gene Search Result


Gene Information
Gene Name RANBP2
Gene ID 5903
Gene Full Name RAN binding protein 2
Gene Alias ANE1; TRP1; TRP2; ADANE; IIAE3; NUP358
Transcripts ENSG00000153201
Virus HBV
Gene Type protein coding
HPA Location Info Nuclear membrane;Nucleoplasm;Vesicles;
HPA Protein Class Info Cancer-related genes, Disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters
Uniport_ID P49792
HGNC ID HGNC:9848
VEGA ID OTTHUMG00000130981
OMIM ID 601181
String ID 9606.ENSP00000283195
PharmGKB ID PA34209
Target gene [RANBP2] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1000904 chr2 894 93 302 1289 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE114783 (GEO) Chronic HBV (CHB) infection 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Hepatocellular carcinoma 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Liver cirrhosis 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: GSE114783

HeatMap of cell type fractions in all samples Lollipop of RANBP2 expression and immune infiltrating cell level correlation result in HBV+ Chronic HBV (CHB) infection samples
RANBP2 expression: Low -> High
Lollipop of RANBP2 expression and immune infiltrating cell level correlation result in HBV+ Liver cirrhosis samples Lollipop of RANBP2 expression and immune infiltrating cell level correlation result in HBV+ Hepatocellular carcinoma samples

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of RANBP2 expression and immune infiltrating cell level correlation result in HBV+ samples
RANBP2 expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).