HIV Target gene Detail Information

> RALGPS2 Gene Search Result

Gene Information

Gene Name	RALGPS2
Gene ID	55103
Gene Full Name	Ral GEF with PH domain and SH3 binding motif 2
Gene Alias	dJ595C2.1
Transcripts	ENSG00000116191
Virus	HIV
Gene Type	protein coding
HPA Location Info	Cytosol;Nucleoplasm;
HPA Protein Class Info	Disease related genes, Predicted intracellular proteins
Uniport_ID	Q86X27
HGNC ID	HGNC:30279
VEGA ID	OTTHUMG00000035076
OMIM ID	617819
String ID	9606.ENSP00000356607
PharmGKB ID	PA134864387

Target gene [RALGPS2] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4005346	chr1	5	23	7	35	View
4005347	chr1	5	23	7	35	View
4005348	chr1	5	23	7	35	View
4005531	chr1	3	21	7	31	View
4005532	chr1	3	21	7	31	View
4012185	chr1	4	1		5	View
4016127	chr1				0	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of RALGPS2 expression and immune infiltrating cell level correlation result in HIV+ samples
RALGPS2 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of RALGPS2 expression and immune infiltrating cell level correlation result in HIV+ samples
RALGPS2 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).