HIV Target gene Detail Information

> RAD51C Gene Search Result

Gene Information

Gene Name	RAD51C
Gene ID	5889
Gene Full Name	RAD51 paralog C
Gene Alias	FANCO; R51H3; BROVCA3; RAD51L2
Transcripts	ENSG00000108384
Virus	HIV
Gene Type	protein coding
HPA Location Info	Cytosol;Mitochondria;Nucleoplasm;Cell Junctions;Vesicles;
HPA Protein Class Info	Disease related genes, Predicted intracellular proteins
Gene Function	Suppressor gene
Uniport_ID	O43502
HGNC ID	HGNC:9820
VEGA ID	OTTHUMG00000141292
OMIM ID	602774
String ID	9606.ENSP00000336701
PharmGKB ID	PA34177

Target gene [RAD51C] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4009936	chr17	10			10	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of RAD51C expression and immune infiltrating cell level correlation result in HIV+ samples
RAD51C expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of RAD51C expression and immune infiltrating cell level correlation result in HIV+ samples
RAD51C expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).