HIV Target gene Detail Information

> RAD51B Gene Search Result

Gene Information

Gene Name	RAD51B
Gene ID	5890
Gene Full Name	RAD51 paralog B
Gene Alias	REC2; R51H2; RAD51L1
Transcripts	ENSG00000182185
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nuclear bodies;Nucleoplasm;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Cancer-related genes, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID	O15315
HGNC ID	HGNC:9822
VEGA ID	OTTHUMG00000157530
OMIM ID	602948
String ID	9606.ENSP00000419471
PharmGKB ID	PA34178

Target gene [RAD51B] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4001742	chr14	74	34	27	135	View
4007187	chr14	18	2		20	View
4008674	chr14	11	2	1	14	View
4010829	chr14	8			8	View
4011443	chr14	7			7	View
4013595	chr14		2	1	3	View
4015033	chr14	1			1	View
4015793	chr14		1		1	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of RAD51B expression and immune infiltrating cell level correlation result in HIV+ samples
RAD51B expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).