HIV Target gene Detail Information

> RAD51 Gene Search Result

Gene Information

Gene Name	RAD51
Gene ID	5888
Gene Full Name	RAD51 recombinase
Gene Alias	RECA; BRCC5; FANCR; MRMV2; HRAD51; RAD51A; HsRad51; HsT16930
Transcripts	ENSG00000051180
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nucleoli rim;Cytosol;
HPA Protein Class Info	Cancer-related genes, Disease related genes, Predicted intracellular proteins
Uniport_ID	Q06609
HGNC ID	HGNC:9817
VEGA ID	OTTHUMG00000130067
OMIM ID	179617
String ID	9606.ENSP00000372088
Drugbank ID	BE0002412
PharmGKB ID	PA34176

Target gene [RAD51] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4010999	chr15	4	3		7	View
4014694	chr15	1		1	2	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of RAD51 expression and immune infiltrating cell level correlation result in HIV+ samples
RAD51 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of RAD51 expression and immune infiltrating cell level correlation result in HIV+ samples
RAD51 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).