HIV Target gene Detail Information

> RAD18 Gene Search Result

Gene Information

Gene Name	RAD18
Gene ID	56852
Gene Full Name	RAD18, E3 ubiquitin protein ligase
Gene Alias	RNF73
Transcripts	ENSG00000070950
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nuclear bodies;Nucleoplasm;
HPA Protein Class Info	Enzymes, Plasma proteins, Predicted intracellular proteins
Uniport_ID	Q9NS91
HGNC ID	HGNC:18278
VEGA ID	OTTHUMG00000090545
OMIM ID	605256
String ID	9606.ENSP00000264926
PharmGKB ID	PA134912253

Target gene [RAD18] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4011750	chr3	6			6	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of RAD18 expression and immune infiltrating cell level correlation result in HIV+ samples
RAD18 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).