HIV Target gene Detail Information

> RACGAP1 Gene Search Result

Gene Information

Gene Name	RACGAP1
Gene ID	29127
Gene Full Name	Rac GTPase activating protein 1
Gene Alias	CYK4; ID-GAP; HsCYK-4; MgcRacGAP
Transcripts	ENSG00000161800
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nucleoplasm;
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	Q9H0H5
HGNC ID	HGNC:9804
VEGA ID	OTTHUMG00000169811
OMIM ID	604980
String ID	9606.ENSP00000404190
PharmGKB ID	PA34165

Target gene [RACGAP1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4001999	chr12	42	20	56	118	View
4003010	chr12	12	60		72	View
4008923	chr12	12	1		13	View
4008924	chr12	13			13	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of RACGAP1 expression and immune infiltrating cell level correlation result in HIV+ samples
RACGAP1 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of RACGAP1 expression and immune infiltrating cell level correlation result in HIV+ samples
RACGAP1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).