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HBV Target gene Detail Information

> RABGAP1L Gene Search Result


Gene Information
Gene Name RABGAP1L
Gene ID 9910
Gene Full Name RAB GTPase activating protein 1 like
Gene Alias HHL; TBC1D18
Transcripts ENSG00000152061
Virus HBV
Gene Type protein coding
HPA Location Info
Membrane Info Predicted membrane proteins
HPA Protein Class Info Disease related genes, Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID B7ZAP0; Q5R372
HGNC ID HGNC:24663
VEGA ID OTTHUMG00000034899
OMIM ID 609238
String ID 9606.ENSP00000251507
PharmGKB ID PA134940645
Target gene [RABGAP1L] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1006637 chr1 34 2 36 View
1014669 chr1 3 3 View
1015367 chr1 1 1 2 View
1019413 chr1 0 View
1019414 chr1 0 View
1019578 chr1 0 View
1404609 chr1 66 52 23 141 View
1405014 chr1 16 2 18 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE114783 (GEO) Chronic HBV (CHB) infection 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Hepatocellular carcinoma 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Liver cirrhosis 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: GSE114783

HeatMap of cell type fractions in all samples Lollipop of RABGAP1L expression and immune infiltrating cell level correlation result in HBV+ Chronic HBV (CHB) infection samples
RABGAP1L expression: Low -> High
Lollipop of RABGAP1L expression and immune infiltrating cell level correlation result in HBV+ Liver cirrhosis samples Lollipop of RABGAP1L expression and immune infiltrating cell level correlation result in HBV+ Hepatocellular carcinoma samples

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of RABGAP1L expression and immune infiltrating cell level correlation result in HBV+ samples
RABGAP1L expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).