HIV Target gene Detail Information

> RABEP1 Gene Search Result

Gene Information

Gene Name	RABEP1
Gene ID	9135
Gene Full Name	rabaptin, RAB GTPase binding effector protein 1
Gene Alias	RAB5EP; RABPT5
Transcripts	ENSG00000029725
Virus	HIV
Gene Type	protein coding
HPA Location Info	Vesicles;
HPA Protein Class Info	Cancer-related genes, Predicted intracellular proteins
Uniport_ID	Q15276
HGNC ID	HGNC:17677
VEGA ID	OTTHUMG00000177870
OMIM ID	603616
String ID	9606.ENSP00000445408
PharmGKB ID	PA134884097

Target gene [RABEP1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4000476	chr17	300	75	61	436	View
4002707	chr17	83			83	View
4003097	chr17	69			69	View
4004365	chr17	35	10		45	View
4004775	chr17	17	20	2	39	View
4006046	chr17	3	9	15	27	View
4009232	chr17	11	1		12	View
4010702	chr17	8			8	View
4012729	chr17	4			4	View
4013353	chr17	3			3	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of RABEP1 expression and immune infiltrating cell level correlation result in HIV+ samples
RABEP1 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of RABEP1 expression and immune infiltrating cell level correlation result in HIV+ samples
RABEP1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).