HIV Target gene Detail Information

> RAB8B Gene Search Result

Gene Information

Gene Name	RAB8B
Gene ID	51762
Gene Full Name	RAB8B, member RAS oncogene family
Transcripts	ENSG00000166128
Virus	HIV
Gene Type	protein coding
HPA Location Info	Vesicles;Nucleoplasm;
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	Q92930
HGNC ID	HGNC:30273
VEGA ID	OTTHUMG00000132862
OMIM ID	613532
String ID	9606.ENSP00000312734
Drugbank ID	BE0004478
PharmGKB ID	PA134944620

Target gene [RAB8B] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4002829	chr15	68	10		78	View
4003102	chr15	67	2		69	View
4003445	chr15	60	1		61	View
4009534	chr15	11			11	View
4011508	chr15	6			6	View
4016601	chr15				0	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of RAB8B expression and immune infiltrating cell level correlation result in HIV+ samples
RAB8B expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of RAB8B expression and immune infiltrating cell level correlation result in HIV+ samples
RAB8B expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).