HIV Target gene Detail Information

> RAB6B Gene Search Result

Gene Information

Gene Name	RAB6B
Gene ID	51560
Gene Full Name	RAB6B, member RAS oncogene family
Transcripts	ENSG00000154917
Virus	HIV
Gene Type	protein coding
HPA Location Info	Golgi apparatus;
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	Q9NRW1
HGNC ID	HGNC:14902
VEGA ID	OTTHUMG00000159749
OMIM ID	615852
String ID	9606.ENSP00000285208
PharmGKB ID	PA34147

Target gene [RAB6B] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4009159	chr3	11	1		12	View
4010326	chr3	7	2		9	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of RAB6B expression and immune infiltrating cell level correlation result in HIV+ samples
RAB6B expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of RAB6B expression and immune infiltrating cell level correlation result in HIV+ samples
RAB6B expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).