HIV Target gene Detail Information

> RAB6A Gene Search Result

Gene Information

Gene Name	RAB6A
Gene ID	5870
Gene Full Name	RAB6A, member RAS oncogene family
Gene Alias	RAB6
Transcripts	ENSG00000175582
Virus	HIV
Gene Type	protein coding
HPA Location Info	Golgi apparatus;
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	P20340
HGNC ID	HGNC:9786
VEGA ID	OTTHUMG00000134308
OMIM ID	179513
String ID	9606.ENSP00000311449
PharmGKB ID	PA34146

Target gene [RAB6A] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4001358	chr11	174			174	View
4001929	chr11	85	28	10	123	View
4011559	chr11	4	2		6	View
4011825	chr11	4	2		6	View
4012439	chr11	5			5	View
4014338	chr11		2		2	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of RAB6A expression and immune infiltrating cell level correlation result in HIV+ samples
RAB6A expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of RAB6A expression and immune infiltrating cell level correlation result in HIV+ samples
RAB6A expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).