HBV Target gene Detail Information

> RAB5C Gene Search Result

Gene Information

Gene Name	RAB5C
Gene ID	5878
Gene Full Name	RAB5C, member RAS oncogene family
Gene Alias	RABL; L1880; RAB5L; RAB5CL
Transcripts	ENSG00000108774
Virus	HBV
Gene Type	protein coding
HPA Location Info	Endosomes;
HPA Protein Class Info	Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins
Uniport_ID	P51148
HGNC ID	HGNC:9785
VEGA ID	OTTHUMG00000169703
OMIM ID	604037
String ID	9606.ENSP00000447053
PharmGKB ID	PA34145

Target gene [RAB5C] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1004759	chr17	70			70	View
1009220	chr17	15	2		17	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of RAB5C expression and immune infiltrating cell level correlation result in HBV+ samples
RAB5C expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).