HIV Target gene Detail Information

> RAB5B Gene Search Result

Gene Information

Gene Name	RAB5B
Gene ID	5869
Gene Full Name	RAB5B, member RAS oncogene family
Transcripts	ENSG00000111540
Virus	HIV
Gene Type	protein coding
HPA Location Info	Vesicles;
HPA Protein Class Info	Predicted intracellular proteins, RAS pathway related proteins
Uniport_ID	P61020
HGNC ID	HGNC:9784
VEGA ID	OTTHUMG00000169682
OMIM ID	179514
String ID	9606.ENSP00000353444
PharmGKB ID	PA34144

Target gene [RAB5B] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4000770	chr12	189	35	61	285	View
4000828	chr12	29	241		270	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of RAB5B expression and immune infiltrating cell level correlation result in HIV+ samples
RAB5B expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of RAB5B expression and immune infiltrating cell level correlation result in HIV+ samples
RAB5B expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).