HBV Target gene Detail Information

> RAB5A Gene Search Result


Gene Information
Gene Name RAB5A
Gene ID 5868
Gene Full Name RAB5A, member RAS oncogene family
Gene Alias RAB5
Transcripts ENSG00000144566
Virus HBV
Gene Type protein coding
HPA Location Info Nucleoplasm;Vesicles;
HPA Protein Class Info Predicted intracellular proteins, RAS pathway related proteins
Uniport_ID P20339
HGNC ID HGNC:9783
VEGA ID OTTHUMG00000129889
OMIM ID 179512
String ID 9606.ENSP00000273047
Drugbank ID BE0004533
PharmGKB ID PA34143
Target gene [RAB5A] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1011353 chr3 6 3 9 View
1016591 chr3 1 1 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of RAB5A expression and immune infiltrating cell level correlation result in HBV+ samples
RAB5A expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).