HIV Target gene Detail Information

> RAB3GAP1 Gene Search Result

Gene Information

Gene Name	RAB3GAP1
Gene ID	22930
Gene Full Name	RAB3 GTPase activating protein catalytic subunit 1
Gene Alias	P130; WARBM1; RAB3GAP; RAB3GAP130
Transcripts	ENSG00000115839
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nucleoplasm;Cytosol;
HPA Protein Class Info	Disease related genes, Predicted intracellular proteins
Uniport_ID	Q15042
HGNC ID	HGNC:17063
VEGA ID	OTTHUMG00000154889
OMIM ID	602536
String ID	9606.ENSP00000411418
PharmGKB ID	PA134969639

Target gene [RAB3GAP1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4012288	chr2	2	2	1	5	View
4013896	chr2	3			3	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of RAB3GAP1 expression and immune infiltrating cell level correlation result in HIV+ samples
RAB3GAP1 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of RAB3GAP1 expression and immune infiltrating cell level correlation result in HIV+ samples
RAB3GAP1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).