HIV Target gene Detail Information

> RAB27B Gene Search Result


Gene Information
Gene Name RAB27B
Gene ID 5874
Gene Full Name RAB27B, member RAS oncogene family
Gene Alias C25KG
Transcripts ENSG00000041353
Virus HIV
Gene Type protein coding
HPA Location Info Golgi apparatus;Plasma membrane;Cytosol;
HPA Protein Class Info Plasma proteins, Predicted intracellular proteins
Uniport_ID O00194
HGNC ID HGNC:9767
VEGA ID OTTHUMG00000132710
OMIM ID 603869
String ID 9606.ENSP00000262094
PharmGKB ID PA34118
Target gene [RAB27B] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
4002242 chr18 82 18 3 103 View
4016618 chr18 0 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE17372 (GEO) AIDS-associated lymphoma 17 AIDS-Related Lymphomas (HIV+)(17)

> Dataset: GSE17372

HeatMap of cell type fractions in all samples Lollipop of RAB27B expression and immune infiltrating cell level correlation result in HIV+ samples
RAB27B expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).