HTLV1 Target gene Detail Information

> RAB23 Gene Search Result

Gene Information

Gene Name	RAB23
Gene ID	51715
Gene Full Name	RAB23, member RAS oncogene family
Gene Alias	HSPC137
Transcripts	ENSG00000112210
Virus	HTLV1
Gene Type	protein coding
HPA Location Info	Cytosol;Plasma membrane;
HPA Protein Class Info	Disease related genes, Predicted intracellular proteins
Gene Function	Oncogene
Uniport_ID	Q9ULC3
HGNC ID	HGNC:14263
VEGA ID	OTTHUMG00000014918
OMIM ID	606144
String ID	9606.ENSP00000417610
PharmGKB ID	PA34113

Target gene [RAB23] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
6003212	chr6	8	163	4	175	View
6020453	chr6	4	3		7	View
6021006	chr6	1	5		6	View
6029348	chr6		1		1	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE55851 (GEO)	Adult T-cell leukemia	21	Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)
GSE29312 (GEO)	HTLV-1 associated myelopathy	39	Normal (9), Asymptomatic carriers (HTLV1+)(20), HTLV-1-associated myelopathy (HTLV1+)(10)
GSE29332 (GEO)	HTLV-1 associated myelopathy	35	Normal (8), Asymptomatic carriers (HTLV1+)(17), HTLV-1-associated myelopathy (HTLV1+)(10)

> Dataset: GSE55851
HeatMap of cell type fractions in all samples	Lollipop of RAB23 expression and immune infiltrating cell level correlation result in HTLV1+ samples
RAB23 expression: Low -> High

> Dataset: GSE29312
HeatMap of cell type fractions in all samples	Lollipop of RAB23 expression and immune infiltrating cell level correlation result in HTLV1+ samples
RAB23 expression: Low -> High

> Dataset: GSE29332
HeatMap of cell type fractions in all samples	Lollipop of RAB23 expression and immune infiltrating cell level correlation result in HTLV1+ samples
RAB23 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).