HTLV1 Target gene Detail Information

> RAB1B Gene Search Result

Gene Information

Gene Name	RAB1B
Gene ID	81876
Gene Full Name	RAB1B, member RAS oncogene family
Transcripts	ENSG00000174903
Virus	HTLV1
Gene Type	protein coding
HPA Location Info	Golgi apparatus;Endoplasmic reticulum;
HPA Protein Class Info	Plasma proteins, Predicted intracellular proteins
Uniport_ID	Q9H0U4
HGNC ID	HGNC:18370
VEGA ID	OTTHUMG00000166916
OMIM ID	612565
String ID	9606.ENSP00000310226
PharmGKB ID	PA34108

Target gene [RAB1B] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
6003244	chr11	170	2		172	View
6003246	chr11	170	2		172	View
6003247	chr11	170	2		172	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE55851 (GEO)	Adult T-cell leukemia	21	Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)
GSE29312 (GEO)	HTLV-1 associated myelopathy	39	Normal (9), Asymptomatic carriers (HTLV1+)(20), HTLV-1-associated myelopathy (HTLV1+)(10)
GSE29332 (GEO)	HTLV-1 associated myelopathy	35	Normal (8), Asymptomatic carriers (HTLV1+)(17), HTLV-1-associated myelopathy (HTLV1+)(10)

> Dataset: GSE55851
HeatMap of cell type fractions in all samples	Lollipop of RAB1B expression and immune infiltrating cell level correlation result in HTLV1+ samples
RAB1B expression: Low -> High

> Dataset: GSE29312
HeatMap of cell type fractions in all samples	Lollipop of RAB1B expression and immune infiltrating cell level correlation result in HTLV1+ samples
RAB1B expression: Low -> High

> Dataset: GSE29332
HeatMap of cell type fractions in all samples	Lollipop of RAB1B expression and immune infiltrating cell level correlation result in HTLV1+ samples
RAB1B expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).