HIV Target gene Detail Information

> RAB1A Gene Search Result

Gene Information

Gene Name	RAB1A
Gene ID	5861
Gene Full Name	RAB1A, member RAS oncogene family
Gene Alias	RAB1; YPT1
Transcripts	ENSG00000138069
Virus	HIV
Gene Type	protein coding
HPA Location Info	Cytosol;Endoplasmic reticulum;
HPA Protein Class Info	Plasma proteins, Predicted intracellular proteins
Uniport_ID	P62820
HGNC ID	HGNC:9758
VEGA ID	OTTHUMG00000152725
OMIM ID	179508
String ID	9606.ENSP00000387286
PharmGKB ID	PA34107

Target gene [RAB1A] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4003770	chr2	23	9	23	55	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of RAB1A expression and immune infiltrating cell level correlation result in HIV+ samples
RAB1A expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of RAB1A expression and immune infiltrating cell level correlation result in HIV+ samples
RAB1A expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).