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HBV Target gene Detail Information

> PXDN Gene Search Result


Gene Information
Gene Name PXDN
Gene ID 7837
Gene Full Name peroxidasin
Gene Alias PXN; VPO; MG50; PRG2; ASGD7; COPOA; D2S448; D2S448E
Transcripts ENSG00000130508
Virus HBV
Gene Type protein coding
HPA Location Info
HPA Protein Class Info Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins
Uniport_ID Q92626
HGNC ID HGNC:14966
VEGA ID OTTHUMG00000059697
OMIM ID 605158
String ID 9606.ENSP00000252804
PharmGKB ID PA128394535
Target gene [PXDN] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1000485 chr2 908 489 698 2095 View
1008943 chr2 13 5 18 View
1008944 chr2 14 4 18 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE114783 (GEO) Chronic HBV (CHB) infection 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Hepatocellular carcinoma 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Liver cirrhosis 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: GSE114783

HeatMap of cell type fractions in all samples Lollipop of PXDN expression and immune infiltrating cell level correlation result in HBV+ Chronic HBV (CHB) infection samples
PXDN expression: Low -> High
Lollipop of PXDN expression and immune infiltrating cell level correlation result in HBV+ Liver cirrhosis samples Lollipop of PXDN expression and immune infiltrating cell level correlation result in HBV+ Hepatocellular carcinoma samples

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of PXDN expression and immune infiltrating cell level correlation result in HBV+ samples
PXDN expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).