HBV Target gene Detail Information

> PURG Gene Search Result


Gene Information
Gene Name PURG
Gene ID 29942
Gene Full Name purine rich element binding protein G
Gene Alias PURGA; PURGB; PURG-A; PURG-B
Transcripts ENSG00000172733
Virus HBV
Gene Type protein coding
HPA Location Info Nucleoplasm;Plasma membrane;Nucleoli;
HPA Protein Class Info Predicted intracellular proteins, Transcription factors
Uniport_ID Q9UJV8
HGNC ID HGNC:17930
VEGA ID OTTHUMG00000157357
OMIM ID 618041
String ID 9606.ENSP00000418721
PharmGKB ID PA134879671
Target gene [PURG] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1011869 chr8 6 1 1 8 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of PURG expression and immune infiltrating cell level correlation result in HBV+ samples
PURG expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).