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HBV Target gene Detail Information

> PTPRZ1 Gene Search Result


Gene Information
Gene Name PTPRZ1
Gene ID 5803
Gene Full Name protein tyrosine phosphatase, receptor type Z1
Gene Alias PTPZ; HPTPZ; PTP18; PTPRZ; RPTPB; HPTPzeta; PTP-ZETA; RPTPbeta; phosphacan; R-PTP-zeta-2
Transcripts ENSG00000106278
Virus HBV
Gene Type protein coding
HPA Location Info Cytosol;Vesicles;Predicted to be secreted;
Membrane Info Predicted membrane proteins
HPA Protein Class Info Enzymes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins
Uniport_ID P23471
HGNC ID HGNC:9685
VEGA ID OTTHUMG00000157057
OMIM ID 176891
String ID 9606.ENSP00000377047
PharmGKB ID PA34029
Target gene [PTPRZ1] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1014960 chr7 2 1 3 View
1016511 chr7 1 1 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of PTPRZ1 expression and immune infiltrating cell level correlation result in HBV+ samples
PTPRZ1 expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).