HBV Target gene Detail Information

> PTPRR Gene Search Result


Gene Information
Gene Name PTPRR
Gene ID 5801
Gene Full Name protein tyrosine phosphatase, receptor type R
Gene Alias PTPRQ; EC-PTP; PCPTP1; PTP-SL; PTPBR7
Transcripts ENSG00000153233
Virus HBV
Gene Type protein coding
HPA Location Info Cell Junctions;Cytosol;Plasma membrane;
Membrane Info Predicted membrane proteins
HPA Protein Class Info Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID Q15256
HGNC ID HGNC:9680
VEGA ID OTTHUMG00000169502
OMIM ID 602853
String ID 9606.ENSP00000283228
PharmGKB ID PA34025
Target gene [PTPRR] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1001723 chr12 373 45 97 515 View
1006976 chr12 23 9 32 View
1010293 chr12 11 2 13 View
1011196 chr12 10 10 View
1011427 chr12 6 3 9 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of PTPRR expression and immune infiltrating cell level correlation result in HBV+ samples
PTPRR expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).