HBV Target gene Detail Information

> PTPRN2 Gene Search Result


Gene Information
Gene Name PTPRN2
Gene ID 5799
Gene Full Name protein tyrosine phosphatase, receptor type N2
Gene Alias IAR; ICAAR; PTPRP; IA-2beta; R-PTP-N2
Transcripts ENSG00000282185
Virus HBV
Gene Type protein coding
HPA Location Info Vesicles;
Membrane Info Predicted membrane proteins
HPA Protein Class Info Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID Q92932
HGNC ID HGNC:9677
VEGA ID OTTHUMG00000190543
OMIM ID 601698
String ID 9606.ENSP00000374069
PharmGKB ID PA34022
Target gene [PTPRN2] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1003014 chr7 159 15 2 176 View
1013162 chr7 5 5 View
1016164 chr7 1 1 View
1404517 chr7 45 6 51 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of PTPRN2 expression and immune infiltrating cell level correlation result in HBV+ samples
PTPRN2 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).