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HBV Target gene Detail Information

> PTPRM Gene Search Result


Gene Information
Gene Name PTPRM
Gene ID 5797
Gene Full Name protein tyrosine phosphatase, receptor type M
Gene Alias RPTPM; RPTPU; PTPRL1; hR-PTPu; R-PTP-MU
Transcripts ENSG00000173482
Virus HBV
Gene Type protein coding
HPA Location Info Plasma membrane;
Membrane Info Predicted membrane proteins
HPA Protein Class Info Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID P28827
HGNC ID HGNC:9675
VEGA ID OTTHUMG00000131575
OMIM ID 176888
String ID 9606.ENSP00000463325
PharmGKB ID PA34020
Target gene [PTPRM] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1005449 chr18 18 36 54 View
1008236 chr18 20 2 22 View
1010516 chr18 2 10 12 View
1015525 chr18 2 2 View
1019439 chr18 0 View
1404916 chr18 13 1 14 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of PTPRM expression and immune infiltrating cell level correlation result in HBV+ samples
PTPRM expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).