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HBV Target gene Detail Information

> PTPRJ Gene Search Result


Gene Information
Gene Name PTPRJ
Gene ID 5795
Gene Full Name protein tyrosine phosphatase, receptor type J
Gene Alias DEP1; SCC1; CD148; HPTPeta; R-PTP-ETA
Transcripts ENSG00000149177
Virus HBV
Gene Type protein coding
HPA Location Info
Membrane Info Predicted membrane proteins
HPA Protein Class Info CD markers, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins
Gene Function Suppressor gene
Uniport_ID Q12913
HGNC ID HGNC:9673
VEGA ID OTTHUMG00000166573
OMIM ID 600925
String ID 9606.ENSP00000400010
PharmGKB ID PA34018
Target gene [PTPRJ] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1012911 chr11 5 1 6 View
1015874 chr11 1 1 2 View
1017177 chr11 1 1 View
1400323 chr11 48 49 20 117 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of PTPRJ expression and immune infiltrating cell level correlation result in HBV+ samples
PTPRJ expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).