HIV Target gene Detail Information

> PTPRF Gene Search Result


Gene Information
Gene Name PTPRF
Gene ID 5792
Gene Full Name protein tyrosine phosphatase, receptor type F
Gene Alias LAR; BNAH2
Transcripts ENSG00000142949
Virus HIV
Gene Type protein coding
HPA Location Info Golgi apparatus;
Membrane Info Predicted membrane proteins
HPA Protein Class Info Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID P10586
HGNC ID HGNC:9670
VEGA ID OTTHUMG00000007501
OMIM ID 179590
String ID 9606.ENSP00000353030
PharmGKB ID PA34015
Target gene [PTPRF] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
4006293 chr1 21 5 26 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE17372 (GEO) AIDS-associated lymphoma 17 AIDS-Related Lymphomas (HIV+)(17)

> Dataset: GSE17372

HeatMap of cell type fractions in all samples Lollipop of PTPRF expression and immune infiltrating cell level correlation result in HIV+ samples
PTPRF expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).