HIV Target gene Detail Information

> PTPRE Gene Search Result


Gene Information
Gene Name PTPRE
Gene ID 5791
Gene Full Name protein tyrosine phosphatase, receptor type E
Gene Alias PTPE; HPTPE; R-PTP-EPSILON
Transcripts ENSG00000132334
Virus HIV
Gene Type protein coding
HPA Location Info Intermediate filaments;
Membrane Info Predicted membrane proteins
HPA Protein Class Info Enzymes, Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID P23469
HGNC ID HGNC:9669
VEGA ID OTTHUMG00000019254
OMIM ID 600926
String ID 9606.ENSP00000254667
Drugbank ID BE0003568
PharmGKB ID PA34014
Target gene [PTPRE] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
4011308 chr10 7 7 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE17372 (GEO) AIDS-associated lymphoma 17 AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO) HIV-infected disease 44 HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372

HeatMap of cell type fractions in all samples Lollipop of PTPRE expression and immune infiltrating cell level correlation result in HIV+ samples
PTPRE expression: Low -> High

> Dataset: GSE50834

HeatMap of cell type fractions in all samples Lollipop of PTPRE expression and immune infiltrating cell level correlation result in HIV+ samples
PTPRE expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).