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HBV Target gene Detail Information

> PTPRD Gene Search Result


Gene Information
Gene Name PTPRD
Gene ID 5789
Gene Full Name protein tyrosine phosphatase, receptor type D
Gene Alias HPTP; PTPD; HPTPD; HPTPDELTA; RPTPDELTA
Transcripts ENSG00000282932
Virus HBV
Gene Type protein coding
HPA Location Info Vesicles;Nucleoplasm;
Membrane Info Predicted membrane proteins
HPA Protein Class Info Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins
Gene Function Suppressor gene
Uniport_ID P23468
HGNC ID HGNC:9668
VEGA ID OTTHUMG00000021005
OMIM ID 601598
String ID 9606.ENSP00000370593
PharmGKB ID PA34013
Target gene [PTPRD] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1009688 chr9 6 5 4 15 View
1009949 chr9 6 3 5 14 View
1011037 chr9 6 1 3 10 View
1013642 chr9 2 3 5 View
1014299 chr9 2 2 4 View
1015296 chr9 2 2 View
1015415 chr9 2 2 View
1015461 chr9 2 2 View
1015511 chr9 2 2 View
1017623 chr9 0 View
1017629 chr9 0 View
1018074 chr9 0 View
1018125 chr9 0 View
1018594 chr9 0 View
1400266 chr9 15 9 11 35 View
1400703 chr9 0 View
1401112 chr9 1 1 View
1401879 chr9 0 View
1401880 chr9 2 2 View
1404643 chr9 1 11 31 43 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of PTPRD expression and immune infiltrating cell level correlation result in HBV+ samples
PTPRD expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).