HIV Target gene Detail Information

> PTPRA Gene Search Result

Gene Information

Gene Name	PTPRA
Gene ID	5786
Gene Full Name	protein tyrosine phosphatase, receptor type A
Gene Alias	LRP; HLPR; PTPA; HEPTP; HPTPA; RPTPA; PTPRL2; HPTPalpha; R-PTP-alpha
Transcripts	ENSG00000132670
Virus	HIV
Gene Type	protein coding
HPA Location Info	Vesicles;Nucleoplasm;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID	P18433
HGNC ID	HGNC:9664
VEGA ID	OTTHUMG00000031718
OMIM ID	176884
String ID	9606.ENSP00000369756
PharmGKB ID	PA34009

Target gene [PTPRA] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4000464	chr20	25	52	368	445	View
4003155	chr20	8	37	23	68	View
4007058	chr20	19	2		21	View
4008205	chr20	15	1		16	View
4009624	chr20	5	6		11	View
4014623	chr20	2			2	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of PTPRA expression and immune infiltrating cell level correlation result in HIV+ samples
PTPRA expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of PTPRA expression and immune infiltrating cell level correlation result in HIV+ samples
PTPRA expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).