HBV Target gene Detail Information

> PTPN5 Gene Search Result

Gene Information

Gene Name	PTPN5
Gene ID	84867
Gene Full Name	protein tyrosine phosphatase, non-receptor type 5
Gene Alias	STEP; STEP61; PTPSTEP
Transcripts	ENSG00000110786
Virus	HBV
Gene Type	protein coding
HPA Location Info	Endoplasmic reticulum;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID	P54829
HGNC ID	HGNC:9657
VEGA ID	OTTHUMG00000134304
OMIM ID	176879
String ID	9606.ENSP00000351342
PharmGKB ID	PA34001

Target gene [PTPN5] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1011237	chr11	5	4		9	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of PTPN5 expression and immune infiltrating cell level correlation result in HBV+ samples
PTPN5 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).