HIV Target gene Detail Information

> PTPN23 Gene Search Result

Gene Information

Gene Name	PTPN23
Gene ID	25930
Gene Full Name	protein tyrosine phosphatase, non-receptor type 23
Gene Alias	HDPTP; HD-PTP; PTP-TD14
Transcripts	ENSG00000076201
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nuclear bodies;Nucleoplasm;Vesicles;
HPA Protein Class Info	Enzymes, Predicted intracellular proteins
Gene Function	Suppressor gene
Uniport_ID	Q9H3S7
HGNC ID	HGNC:14406
VEGA ID	OTTHUMG00000133520
OMIM ID	606584
String ID	9606.ENSP00000265562
PharmGKB ID	PA33996

Target gene [PTPN23] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4003471	chr3	61			61	View
4013686	chr3	2	1		3	View
4016097	chr3				0	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of PTPN23 expression and immune infiltrating cell level correlation result in HIV+ samples
PTPN23 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of PTPN23 expression and immune infiltrating cell level correlation result in HIV+ samples
PTPN23 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).