HBV Target gene Detail Information

> PTPN14 Gene Search Result


Gene Information
Gene Name PTPN14
Gene ID 5784
Gene Full Name protein tyrosine phosphatase, non-receptor type 14
Gene Alias PEZ; PTP36; CATLPH
Transcripts ENSG00000152104
Virus HBV
Gene Type protein coding
HPA Location Info Nucleoplasm;
HPA Protein Class Info Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins
Uniport_ID Q15678
HGNC ID HGNC:9647
VEGA ID OTTHUMG00000037039
OMIM ID 603155
String ID 9606.ENSP00000355923
PharmGKB ID PA33989
Target gene [PTPN14] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1007729 chr1 2 22 1 25 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of PTPN14 expression and immune infiltrating cell level correlation result in HBV+ samples
PTPN14 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).