HIV Target gene Detail Information

> PTPN13 Gene Search Result

Gene Information

Gene Name	PTPN13
Gene ID	5783
Gene Full Name	protein tyrosine phosphatase, non-receptor type 13
Gene Alias	PNP1; FAP-1; PTP1E; PTPL1; PTPLE; PTP-BL; hPTP1E; PTP-BAS
Transcripts	ENSG00000163629
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nucleoplasm;Cytosol;Nucleoli fibrillar center;
HPA Protein Class Info	Cancer-related genes, Enzymes, Predicted intracellular proteins
Gene Function	Suppressor gene
Uniport_ID	Q12923
HGNC ID	HGNC:9646
VEGA ID	OTTHUMG00000160968
OMIM ID	600267
String ID	9606.ENSP00000394794
PharmGKB ID	PA33988

Target gene [PTPN13] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4008050	chr4	2	14		16	View
4016351	chr4				0	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of PTPN13 expression and immune infiltrating cell level correlation result in HIV+ samples
PTPN13 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of PTPN13 expression and immune infiltrating cell level correlation result in HIV+ samples
PTPN13 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).