HBV Target gene Detail Information

> PTPN12 Gene Search Result

Gene Information

Gene Name	PTPN12
Gene ID	5782
Gene Full Name	protein tyrosine phosphatase, non-receptor type 12
Gene Alias	PTPG1; PTP-PEST
Transcripts	ENSG00000127947
Virus	HBV
Gene Type	protein coding
HPA Location Info	Cytosol;Plasma membrane;
HPA Protein Class Info	Enzymes, Predicted intracellular proteins
Gene Function	Suppressor gene
Uniport_ID	Q05209
HGNC ID	HGNC:9645
VEGA ID	OTTHUMG00000023501
OMIM ID	600079
String ID	9606.ENSP00000248594
Drugbank ID	BE0010319; BE0009940
PharmGKB ID	PA33987

Target gene [PTPN12] related to virus gene/protein/region

ID	PMID	Mutation	Gene/Protein/Region	Description	Detail
1	27075395	G1799C	BCP	G C	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of PTPN12 expression and immune infiltrating cell level correlation result in HBV+ samples
PTPN12 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).

> Dataset: LIHC