HIV Target gene Detail Information

> PTP4A2 Gene Search Result

Gene Information

Gene Name	PTP4A2
Gene ID	8073
Gene Full Name	protein tyrosine phosphatase type IVA, member 2
Gene Alias	HH13; OV-1; PRL2; HH7-2; PRL-2; PTP4A; HU-PP-1; PTPCAAX2; ptp-IV1a; ptp-IV1b
Transcripts	ENSG00000184007
Virus	HIV
Gene Type	protein coding
HPA Location Info
HPA Protein Class Info	Enzymes, Predicted intracellular proteins
Gene Function	Oncogene
Uniport_ID	Q12974
HGNC ID	HGNC:9635
VEGA ID	OTTHUMG00000003801
OMIM ID	601584
String ID	9606.ENSP00000344909
PharmGKB ID	PA33978

Target gene [PTP4A2] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4000231	chr1	106	505	73	684	View
4001005	chr1	11	130	89	230	View
4001848	chr1	4	109	14	127	View
4001985	chr1	16	72	31	119	View
4006406	chr1	25			25	View
4007431	chr1	15	4		19	View
4007487	chr1	19			19	View
4007717	chr1	7	9	2	18	View
4008586	chr1	13	1		14	View
4008746	chr1	10	3	1	14	View
4009311	chr1	12			12	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of PTP4A2 expression and immune infiltrating cell level correlation result in HIV+ samples
PTP4A2 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of PTP4A2 expression and immune infiltrating cell level correlation result in HIV+ samples
PTP4A2 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).